“The overall goal of this study is to design a user-centered design app linked to a smart pill box for people living with HIV (PLWH) and evaluate its effects in a randomized controlled trial. The proposed trial is scientifically significant in representing a principled and systematic effort to test the efficacy of a smartphone intervention linked to a smart pill box for antiretroviral (ART) adherence in PLWH in the United States (US). Guided by a strong theoretical framework building on earlier user-centered design work and integrating a real-time monitoring device, this work has the potential to improve ART adherence in PLWH and have a sustainable public health impact.
Human Immunodeficiency virus (HIV) continues to affect 1.2 million Americans. Achieving viral suppression through adherence to antiretroviral (ART) therapy is a critical determinant of successful transmission prevention and long-term outcomes in HIV-infected patients. However only about 25% of persons living with HIV (PLWH) in the US are virally suppressed, demonstrating the need for effective interventions that enhance ART adherence. mHealth is a tool that has proven useful in supporting behavior change, but most mHealth tools for PLWH have not been well-developed or evaluated. Given the dearth of useful and likeable apps, the need for improving medication adherence in PLWH, and the great promise of mHealth, the investigators propose to build and test a user-centered smartphone app linked to a smart pill box targeting ART adherence in PLWH. Self-report of medication adherence is often criticized since it typically overestimated adherence especially in unmasked trials. Current adherence assessments, such as patient recall, pill counts and pharmacy refill data, typically detect missed doses long after they occur. This study will use real-time, wireless monitoring strategies via the Wisepill dispenser, for measuring ART adherence.” (Source: NCT03205982)
PainPac's objective is to demonstrate that a mobile app intervention, when compared to standard video conferencing sessions, is feasible and a promising strategy to decrease pain in patients with cancer.
The OFSET Study is testing the addition of chemotherapy to the usual treatment of ovarian function suppression plus hormonal therapy in premenopausal ER-positive/HER2negative breast cancer patients who are at high risk of cancer returning.
This study will explore feasibility of using a daily mobile mindfulness app to cope with stress. Digital health data collection procedures including wrist-worn devices and ecological momentary assessments will also be examined.
This research study is being done to monitor common symptoms and behavior, and to provide information and peer support, as well as research opportunities for young women who have been diagnosed with breast cancer.
The Behavior Design in Heart Failure pilot study was conducted over a 6 month period in collaboration with Medtronic and Duke's Center for Advanced Hindsight (CAH). The primary aim of the pilot was to understand if CHF patients would act on instructions provided by a mobile app.
The transcendental meditation program aims to help healthcare workers learn transcendental meditation as a means of coping with stress, anxiety, and depression. This program is also being researched for providers treating patients with COVID-19.
The proposed research advances the health and wellbeing of young adult cancer survivors by creating a developmentally appropriate hybrid in-person/mHealth behavioral symptom management intervention which addresses variables consistently linked to significant social, economic, and health burden.
The objective of the SWET-RA randomized controlled trial is to determine the effects of a 16-week remotely delivered weight loss and exercise training intervention on traditional and inflammatory RA CVD risk factors, disease activity, and patient-reported outcomes in older persons with RA and overweight/obesity.
This research study included the development and pilot testing of a hybrid in-person and mHealth coping skills training intervention for symptom management and daily steps in stem cell transplant patients.
The SHEETS study will examine the feasibility, acceptability, and effectiveness of two digital sleep interventions in improving sleep regularity and psychiatric health during a critical period of adolescence.
The purpose of this study is to examine underlying physical resilience (the ability to bounce back) in response to a specific stressor (total knee replacement). The study is using Pattern's platform to collect biometric data through our Garmin integration.
LIFT is a self-guided treatment program that aims to improve quality of life, reduce symptoms, help gain independence quicker, and build stronger relationships. LIFT uses a mobile app to deliver automated yet personalized support and minfulness training.
The INTENT study is a partnership between Before Brands SpoonfulOne (SO) and DCRI to determine if feeding of SO to infants between 4 and 18 months of age will decrease the likelihood of developing food allergies between 12 and 18 months of age.
The purpose of this study is to evaluate how different types of physical activity and nutrition education and support (in addition to normal clinical care) affect children's health. Pattern's platform and integrations are used for remote activity monitoring.
Fit Together works with adolescents through parks and recreation departments to encourage exercise and track their attendance to scheduled sessions. The program delivers evidence-based recommendations for minority and low-income children with obesity.
EMPOWER is a virtual care program to Engage, inforM, Probe, prOmote Wellness, and fostEr community among patients with Rare diseases. The research project will initially focus on Interstitial Lung Disease (ILD) patients before expanding to a wider range of rare diseases.
This fully virtual study to investigate how a dyad linked incentive strategy compares to individual incentives for patients taking a single medication. Dyad-linked incentives work by jointly rewarding two linked individuals for both adhering to their medication regimen, adding both social support and peer accountability to traditional incentive structures.
VCU's COVID-19 Vaccine Decision Aid consists of a set of questions and branching logic rules based on the users' selections. The web-based aid provides participants with a personalized recommendation on why the COVID-19 vaccine is important for them or if it isn’t appropriate.
This 3-month randomized, double-blind, placebo-controlled trial assesses the effects of combining daily blueberry intake with weekly exercise (BB-EX) on cardiovascular function, as well as physical activity and cognitive function, in sedentary older adults (>60 years).
CONNECT-HF is a large, multi-site research study that includes an ancillary study/app designed to support guideline-based activities to help patients manage heart failure. The Pattern-powered app tracked key biometrics and delivered personalized educational content about heart failure and help patients manage taking their medication.
The ARC measure captures primary care providers' (PCP) ability to appropriately diagnose rare cancers as well as barriers to the appropriate referral of rare cancer patients from primary to specialty care. The results enable practices to better educate providers and ensure patients receive timely care.
Blueprint is a month-long mobile app-based adaptive coping skills training intervention delivered through the Pattern Health app designed to help patients cope with psychological distress symptoms after hospitalization.