WiseApp - Pattern Health

WiseApp is a remote care program and research study powered by

The overall goal of the WiseApp study is to design a user-centered design app linked to a smart pill box for people living with HIV (PLWH) and evaluate its effects in a randomized controlled trial.

Principle Investigators: Rebecca Schnall, PhD, MPH, RN-BC, FAAN

Institution: Columbia University Medical Center

Tags:

Clinicaltrials.gov Identifiers: NCT03205982

Trial Design: Multi-Site, Hybrid

“The overall goal of this study is to design a user-centered design app linked to a smart pill box for people living with HIV (PLWH) and evaluate its effects in a randomized controlled trial. The proposed trial is scientifically significant in representing a principled and systematic effort to test the efficacy of a smartphone intervention linked to a smart pill box for antiretroviral (ART) adherence in PLWH in the United States (US). Guided by a strong theoretical framework building on earlier user-centered design work and integrating a real-time monitoring device, this work has the potential to improve ART adherence in PLWH and have a sustainable public health impact.

Human Immunodeficiency virus (HIV) continues to affect 1.2 million Americans. Achieving viral suppression through adherence to antiretroviral (ART) therapy is a critical determinant of successful transmission prevention and long-term outcomes in HIV-infected patients. However only about 25% of persons living with HIV (PLWH) in the US are virally suppressed, demonstrating the need for effective interventions that enhance ART adherence. mHealth is a tool that has proven useful in supporting behavior change, but most mHealth tools for PLWH have not been well-developed or evaluated. Given the dearth of useful and likeable apps, the need for improving medication adherence in PLWH, and the great promise of mHealth, the investigators propose to build and test a user-centered smartphone app linked to a smart pill box targeting ART adherence in PLWH. Self-report of medication adherence is often criticized since it typically overestimated adherence especially in unmasked trials. Current adherence assessments, such as patient recall, pill counts and pharmacy refill data, typically detect missed doses long after they occur. This study will use real-time, wireless monitoring strategies via the Wisepill dispenser, for measuring ART adherence.” (Source: NCT03205982)

Related Publications

Looking for a technology partner to power your research? Let's talk.

Other Relevant Research Projects

Transcendental Meditation Program for Providers

The transcendental meditation program aims to help healthcare workers learn transcendental meditation as a means of coping with stress, anxiety, and depression. This program is also being researched for providers treating patients with COVID-19.

Symptom Management for YA Cancer Survivors

The proposed research advances the health and wellbeing of young adult cancer survivors by creating a developmentally appropriate hybrid in-person/mHealth behavioral symptom management intervention which addresses variables consistently linked to significant social, economic, and health burden.

SWET

The objective of the SWET-RA randomized controlled trial is to determine the effects of a 16-week remotely delivered weight loss and exercise training intervention on traditional and inflammatory RA CVD risk factors, disease activity, and patient-reported outcomes in older persons with RA and overweight/obesity.

Step Up

This research study included the development and pilot testing of a hybrid in-person and mHealth coping skills training intervention for symptom management and daily steps in stem cell transplant patients.

SHEETS

The SHEETS study will examine the feasibility, acceptability, and effectiveness of two digital sleep interventions in improving sleep regularity and psychiatric health during a critical period of adolescence.

Reboot

Reboot is a perioperative program to improve therapy compliance and outcomes for heart transplant patients.

REMOTE HF-ACTION

The REMOTE HF-ACTION study aims to test a remote cardiac rehab program using device data from patients' implantable devices (pace makers, defibrillators).

PRIME-Knee

The purpose of this study is to examine underlying physical resilience (the ability to bounce back) in response to a specific stressor (total knee replacement). The study is using Pattern's platform to collect biometric data through our Garmin integration.

POWER

POWER is designed to improve patient outcomes by giving surgical patients prehabilitation before undergoing major abdominal operations.

P-MAPP

The P-MAPP study is evaluating an education and care plan aimed at improving medication adherence in patients with Type 2 diabetes.

Orthopedic Opioid Risk Management

This program collects opioid usage data from participants post-hip surgery and uses an algorithm to identify and stratify patients at risk for opioid-induced respiratory depression.

Nourish

The Nourish program assesses the use of nutritional coaching to improve adherence to the DASH diet in patients managing high blood pressure.

mCOPE

mCOPE is an innovative mobile health coping skills training protocol that is adapted to meet the multiple symptom needs and stage-of-life challenges faced by young and middle-aged adults with cancer.

Liver Transplant Rehab

Post-transplant management to improve medication adherence, self-efficacy, and knowledge.

LIFT (Mobile Mindfulness Intervention)

LIFT is a self-guided treatment program that aims to improve quality of life, reduce symptoms, help gain independence quicker, and build stronger relationships. LIFT uses a mobile app to deliver automated yet personalized support and minfulness training.

LAPS (Long-Term Antipsychotic Pediatric Safety)

The purpose of this study is to monitor height, weight, and quality of life in children taking antipsychotic medications.

LAMP COVID-19 Testing Program

The LAMP COVID-19 Testing Program is collecting data from users testing an at-home saliva COVID-19 test developed at Stanford.

Kids Heart Program

The Kids Heart team enrolls the parents of children with congenital heart defects in the program to track their children's health activities.

iTransition

iTransition is a multilevel mHealth intervention designed to support youth living with HIV and their pediatric/adolescent and adult care providers.

INTENT

The INTENT study is a partnership between Before Brands SpoonfulOne (SO) and DCRI to determine if feeding of SO to infants between 4 and 18 months of age will decrease the likelihood of developing food allergies between 12 and 18 months of age.

ICAN NC

ICAN NC is a research study and digital intervention developed to support breast cancer patient pain management in underserved medical communities in North Carolina.

Hearts and Parks

The purpose of this study is to evaluate how different types of physical activity and nutrition education and support (in addition to normal clinical care) affect children's health. Pattern's platform and integrations are used for remote activity monitoring.

GROWell

GROWell is a research study and digital intervention promoting postpartum weight loss among women who enter pregnancy overweight or obese.

Fit Together

Fit Together works with adolescents through parks and recreation departments to encourage exercise and track their attendance to scheduled sessions. The program delivers evidence-based recommendations for minority and low-income children with obesity.

EMPOWER

EMPOWER is a virtual care program to Engage, inforM, Probe, prOmote Wellness, and fostEr community among patients with Rare diseases. The research project will initially focus on Interstitial Lung Disease (ILD) patients before expanding to a wider range of rare diseases.

Dyad Linked Incentives

This fully virtual study to investigate how a dyad linked incentive strategy compares to individual incentives for patients taking a single medication. Dyad-linked incentives work by jointly rewarding two linked individuals for both adhering to their medication regimen, adding both social support and peer accountability to traditional incentive structures.

COVID-19 Vaccine Decision Aid

VCU's COVID-19 Vaccine Decision Aid consists of a set of questions and branching logic rules based on the users' selections. The web-based aid provides participants with a personalized recommendation on why the COVID-19 vaccine is important for them or if it isn’t appropriate.

BEACTIVE

This 3-month randomized, double-blind, placebo-controlled trial assesses the effects of combining daily blueberry intake with weekly exercise (BB-EX) on cardiovascular function, as well as physical activity and cognitive function, in sedentary older adults (>60 years).

CONNECT-HF

CONNECT-HF is a large, multi-site research study that includes an ancillary study/app designed to support guideline-based activities to help patients manage heart failure. The Pattern-powered app tracked key biometrics and delivered personalized educational content about heart failure and help patients manage taking their medication.

Awareness of Rare Cancers (ARC) PCP Survey

The ARC measure captures primary care providers' (PCP) ability to appropriately diagnose rare cancers as well as barriers to the appropriate referral of rare cancer patients from primary to specialty care. The results enable practices to better educate providers and ensure patients receive timely care.

Blueprint

Blueprint is a month-long mobile app-based adaptive coping skills training intervention delivered through the Pattern Health app designed to help patients cope with psychological distress symptoms after hospitalization.

View our Research Portfolio

WiseApp (The Wise App Trial for Improving Health Outcomes in PLWH)

Related Publications

Looking for a technology partner to power your research? Let's talk.

Other Relevant Research Projects